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The Trailblazer study: Global Study to Investigate Safety and Efficacy of Donanemab in Early Symptomatic Alzheimer’s Disease

Eastern Clinical Research Unit

This is a phase 3 study to evaluate the safety and efficacy of donanemab in participants with early symptomatic Alzheimer's Disease caused by elevated tau protein in the brain. Data suggests that removing this may result in the slowing of Alzheimer's Disease and this drug has shown potential for achieve this. 

This study has been approved by the Eastern Health Human Research Ethics Committee

Participation

You may be eligible to participate if you meet the following criteria: 

  • aged 60 to 85 years and 
  • have had a gradual change in memory function over 6 months

Visits will include cognitive assessments, blood tests, ECG and MRI scans. 

A study partner who has at least 10 hours of contact with the participant is required to accompany the participant to visits, to provide accurate information about the participant's cognitive and functional abilities over time. 


Participant duration

9 weeks screening, 72 weeks of treatment and 8 weeks of follow up


Available to people living in

Vic


Study begins

Saturday, 1 June 2024


Study ends

Monday, 31 December 2029

Contact

To find out more about this study, contact:

Claire McCarthy

Eastern Clinical Research Unit

ecru.cognitivereferrals@monash.edu

0429 391 043

Vic

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Last updated
3 September 2024